Functional intercalated nanocomposites with chitosan-glutathione-glycylsarcosine and layered double hydroxides for topical ocular drug delivery.

Xu, Tingting; Xu, Xiaoyue; Gu, Yan; Fang, Lei; Cao, Feng

doi:10.2147/ijn.s148104

Public

Functional intercalated nanocomposites with chitosan-glutathione-glycylsarcosine and layered double hydroxides for topical ocular drug delivery.

Shared by NobleBlocks on Jan 1, 2018 • 12:00 AM UTC

Authors:

Tingting Xu

Xiaoyue Xu

Yan Gu

Abstract

BACKGROUND: To enhance ocular bioavailability, the traditional strategies have focused on prolonging precorneal retention and improving corneal permeability by nano-carriers with positive charge, thiolated polymer, absorption enhancer and so on. Glycylsarcosine (GS) as an active target ligand of the...

Subject

active targeting

glycylsarcosine

intercalated nanocomposites

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