Akkermansia muciniphila-derived extracellular vesicles influence gut permeability through the regulation of tight junctions

Chelakkot, Chaithanya; Choi, Youngwoo; Kim, Dae‐Kyum; T Park, Hyun; Ghim, Jaewang; Kwon, Yonghoon; Jeon, Jinseong; Kim, Min-Seon; Jee, Young‐Koo; Song Gho, Yong; Park, Hae‐Sim; Kim, Yoon‐Keun; Ho Ryu, Sung

doi:10.1038/emm.2017.282

Public

Akkermansia muciniphila-derived extracellular vesicles influence gut permeability through the regulation of tight junctions

Published in Experimental & Molecular Medicine • Feb 1, 2018

Authors:

Chaithanya Chelakkot

Youngwoo Choi

Dae‐Kyum Kim

Abstract

The gut microbiota has an important role in the gut barrier, inflammation and metabolic functions. Studies have identified a close association between the intestinal barrier and metabolic diseases, including obesity and type 2 diabetes (T2D). Recently, Akkermansia muciniphila has been reported as a ...

Subject

Akkermansia muciniphila

Occludin

Tight junction

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