PKM2 is involved in neuropathic pain by regulating ERK and STAT3 activation in rat spinal cord.

Background Pyruvate kinase isozymes M2 (PKM2), as a member of pyruvate kinase family, plays a role of glycolytic enzyme in glucose metabolism. It also functions as protein kinase in cell proliferation, signaling, immunity, and gene transcription. In this study, the role of PKM2 in neuropathic pain i... View More