Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes

Zhao, Liping; Zhang, Feng; Ding, Xiaoying; Wu, Guojun; Y. Lam, Yan; Wang, Xuejiao; Fu, Huaqing; Xue, Xinhe; Lu, Chunhua; Ma, Jilin; Yu, Lihua; Xu, Chengmei; Ren, Zhongying; Xu, Ying; Xu, Songmei; Shen, Hongli; Zhu, Xiuli; Shi, Yu; Shen, Qingyun; Dong, Weiping; Liu, Rui; Ling, Yunxia; Zeng, Yue; Wang, Xingpeng; Zhang, Qianpeng; Wang, Jing; Wang, Linghua; Wu, Yanqiu; Zeng, Benhua; Wei, Hong; Zhang, Menghui; Peng, Yongde; Zhang, Chenhong

doi:10.1126/science.aao5774

Public

Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes

Published in Science • Mar 8, 2018

Authors:

Liping Zhao

Feng Zhang

Xiaoying Ding

Abstract

The gut microbiota benefits humans via short-chain fatty acid (SCFA) production from carbohydrate fermentation, and deficiency in SCFA production is associated with type 2 diabetes mellitus (T2DM). We conducted a randomized clinical study of specifically designed isoenergetic diets, together with fe...

Subject

Type 2 diabetes

Prebiotic

Fermentation

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