Complex karyotype in patients with mantle cell lymphoma predicts inferior survival and poor response to intensive induction therapy

Brian Greenwell, I.; D. Staton, Ashley; J. Lee, Michael; M. Switchenko, Jeffrey; F. Saxe, Debra; J. Maly, Joseph; A. Blum, Kristie; S. Grover, Natalie; P. Mathews, Stephanie; J. Gordon, Max; V. Danilov, Alexey; Epperla, Narendranath; S. Fenske, Timothy; Hamadani, Mehdi; I. Park, Steven; R. Flowers, Christopher; B. Cohen, Jonathon

doi:10.1002/cncr.31328

Public

Complex karyotype in patients with mantle cell lymphoma predicts inferior survival and poor response to intensive induction therapy

Shared by NobleBlocks on Mar 26, 2018 • 12:00 AM UTC

Authors:

I. Brian Greenwell

Ashley D. Staton

Michael J. Lee

Abstract

BACKGROUND Risk stratification of newly diagnosed patients with mantle cell lymphoma (MCL) primarily is based on the MCL International Prognostic Index (MIPI) and Ki‐67 proliferative index. Single‐center studies have reported inferior outcomes in patients with a complex karyotype (CK), but this rema...

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