Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours

Ma, Xiaotu; Liu, Yu; Liu, Yanling; B. Alexandrov, Ludmil; N. Edmonson, Michael; Gawad, Charles; Zhou, Xin; Li, Yongjin; Rusch, Michael; Easton, John; Huether, Robert; Gonzalez-Pena, Veronica; R. Wilkinson, Mark; C. Hermida, Leandro; Davis, Sean; Sioson, Edgar; Pounds, Stanley; Cao, Xueyuan; E. Ries, Rhonda; Wang, Zhaoming; Chen, Xiang; Dong, Li; J. Diskin, Sharon; A. Smith, Malcolm; M. Guidry Auvil, Jaime; S. Meltzer, Paul; C. Lau, Ching; J. Perlman, Elizabeth; M. Maris, John; Meshinchi, Soheil; P. Hunger, Stephen; S. Gerhard, Daniela; Zhang, Jinghui

doi:10.1038/nature25795

Public

Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours

Published in Nature • Feb 28, 2018

Authors:

Xiaotu Ma

Yu Liu

Yanling Liu

Abstract

Analysis of molecular aberrations across multiple cancer types, known as pan-cancer analysis, identifies commonalities and differences in key biological processes that are dysregulated in cancer cells from diverse lineages. Pan-cancer analyses have been performed for adult but not paediatric cancers...

Subject

Transcriptome

Biology

Genome

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