CSF biomarkers of Alzheimer's disease concord with amyloid‐β PET and predict clinical progression: A study of fully automated immunoassays in BioFINDER and ADNI cohorts

Hansson, Oskar; Seibyl, John; Stomrud, Erik; Zetterberg, Henrik; Q. Trojanowski, John; Bittner, Tobias; Lifke, Valeria; Corradini, Veronika; Eichenlaub, Udo; Batrla, Richard; Buck, Katharina; Zink, Katharina; Rabe, Christina; Blennow, Kaj; M. Shaw, Leslie; the Swedish BioFINDER study group, for; Disease Neuroimaging Initiative, Alzheimer's

doi:10.1016/j.jalz.2018.01.010

Public

CSF biomarkers of Alzheimer's disease concord with amyloid‐β PET and predict clinical progression: A study of fully automated immunoassays in BioFINDER and ADNI cohorts

Published in Alzheimer s & Dementia • Feb 27, 2018

Authors:

Oskar Hansson

John Seibyl

Erik Stomrud

Abstract

INTRODUCTION: We studied whether fully automated Elecsys cerebrospinal fluid (CSF) immunoassay results were concordant with positron emission tomography (PET) and predicted clinical progression, even with cutoffs established in an independent cohort. METHODS: F]florbetapir PET in Alzheimer's Disease...

Subject

Medicine

Amyloid (mycology)

Biomarker

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