Design, Optimization and Characterization of a Transfersomal Gel Using Miconazole Nitrate for the Treatment of Candida Skin Infections

Qushawy, Mona; M. Nasr, Ali; Abd-Alhaseeb, Mohammed; A. Swidan, Shady

doi:10.3390/pharmaceutics10010026

Public

Design, Optimization and Characterization of a Transfersomal Gel Using Miconazole Nitrate for the Treatment of Candida Skin Infections

Published in Pharmaceutics • Feb 23, 2018

Authors:

Mona Qushawy

Ali M. Nasr

Mohammed Abd-Alhaseeb

Abstract

Miconazole nitrate (MIC) is an antifungal drug used for treatment of superficial fungal infections. However, it has low skin permeability. Hence, the objective of this study was to prepare miconazole nitrate using Transfersomes to overcome the barrier function of the skin. MIC Transfersomes were pre...

Subject

Miconazole Nitrate

Stratum corneum

Miconazole

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