Apabetalone Mediated Epigenetic Modulation is Associated with Favorable Kidney Function and Alkaline Phosphatase Profile in Patients with Chronic Kidney Disease

Kulikowski, Ewelina; Halliday, Christopher; Johansson, Jan; Sweeney, Mike; Lebioda, Kenneth; C.W. Wong, Norman; Haarhaus, Mathias; Brandenburg, Vincent; Beddhu, Srinivasan; Tonelli, Marcello; Zoccali, Carmine; Kalantar‐Zadeh, Kamyar

doi:10.1159/000488257

Public

Apabetalone Mediated Epigenetic Modulation is Associated with Favorable Kidney Function and Alkaline Phosphatase Profile in Patients with Chronic Kidney Disease

Published in Kidney & Blood Pressure Research • Jan 1, 2018

Authors:

Ewelina Kulikowski

Christopher Halliday

Jan Johansson

Abstract

BACKGROUND/AIMS: The association between serum alkaline phosphatase (ALP) with adverse cardiovascular outcomes, in Chronic Kidney Disease (CKD) patients has previously been reported and may be a result of increased vascular calcification and inflammation. Here we report, for the first time, the effe...

Subject

Renal function

Kidney disease

Internal medicine

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