Altered expression of glutamate transporter‐1 and water channel protein aquaporin‐4 in human temporal cortex with Alzheimer's disease

Hoshi, Akihiko; Tsunoda, Ayako; Yamamoto, Toshiyuki; Tada, Mari; Kakita, Akiyoshi; Ugawa, Yoshikazu

doi:10.1111/nan.12475

Public

Altered expression of glutamate transporter‐1 and water channel protein aquaporin‐4 in human temporal cortex with Alzheimer's disease

Published in Neuropathology and Applied Neurobiology • Feb 6, 2018

Authors:

Akihiko Hoshi

Ayako Tsunoda

Toshiyuki Yamamoto

Abstract

AIMS: Glutamate neurotoxicity plays an important role in the pathogenesis of various neurodegenerative disorders. Many studies have demonstrated that glutamate transporter-1 (GLT-1), the dominant astrocytic glutamate transporter, is significantly reduced in the cerebral cortex of patients with Alzhe...

Subject

Neuropil

Glutamate receptor

Aquaporin 4

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!