Roles of PAD4 and NETosis in Experimental Atherosclerosis and Arterial Injury

Franck, G; Mawson, Thomas; J. Folco, Eduardo; Molinaro, Roberto; Ruvkun, Victoria; Engelbertsen, Daniel; Liu, Xin; Tesmenitsky, Yevgenia; Shvartz, Eugenia; K. Sukhova, Galina; Michel, Jean-Baptiste; Nicoletti, Antonino; H. Lichtman, Andrew; D. Wagner, Denisa; Croce, Kevin; Libby, Peter

doi:10.1161/circresaha.117.312494

Public

Roles of PAD4 and NETosis in Experimental Atherosclerosis and Arterial Injury

Published in Circulation Research • Mar 23, 2018

Authors:

G Franck

Thomas Mawson

Eduardo J. Folco

Abstract

RATIONALE: Neutrophils likely contribute to the thrombotic complications of human atheromata. In particular, neutrophil extracellular traps (NETs) could exacerbate local inflammation and amplify and propagate arterial intimal injury and thrombosis. PAD4 (peptidyl arginine deiminase 4) participates i...

Subject

Neutrophil extracellular traps

Inflammation

Bone marrow

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!