Melatonin prevents <scp>D</scp> rp1‐mediated mitochondrial fission in diabetic hearts through <scp>SIRT</scp> 1‐ <scp>PGC</scp> 1α pathway

Ding, Mingge; Feng, Na; Tang, Daishi; Feng, Jiahao; Li, Zeyang; Jia, Min; Liu, Zhenhua; Gu, Xiaoming; Wang, Yuemin; Fu, Feng; Pei, Jianming

doi:10.1111/jpi.12491

Public

Melatonin prevents D rp1‐mediated mitochondrial fission in diabetic hearts through SIRT 1‐ PGC 1α pathway

Published in Journal of Pineal Research • Mar 25, 2018

Authors:

Mingge Ding

Na Feng

Daishi Tang

Abstract

Abstract Myocardial contractile dysfunction is associated with an increase in mitochondrial fission in patients with diabetes. However, whether mitochondrial fission directly promotes diabetes‐induced cardiac dysfunction is still unknown. Melatonin exerts a substantial influence on the regulation of...

Subject

Mitochondrial fission

Melatonin

mitochondrial fusion

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