Apalutamide Treatment and Metastasis-free Survival in Prostate Cancer

R. Smith, Matthew; Saad, Fred; Chowdhury, Simon; Oudard, Stéphane; Hadaschik, Boris; N. Graff, Julie; Olmos, David; N. Mainwaring, Paul; Youl Lee, Ji; Uemura, Hiroji; Lopez‐Gitlitz, Angela; C. Trudel, Géralyn; M. Espina, Byron; Shu, Youyi; C. Park, Youn; Rackoff, Wayne; K. Yu, Margaret; J. Small, Eric

doi:10.1056/nejmoa1715546

Public

Apalutamide Treatment and Metastasis-free Survival in Prostate Cancer

Published in New England Journal of Medicine • Feb 8, 2018

Authors:

Matthew R. Smith

Fred Saad

Simon Chowdhury

Abstract

BACKGROUND: Apalutamide, a competitive inhibitor of the androgen receptor, is under development for the treatment of prostate cancer. We evaluated the efficacy of apalutamide in men with nonmetastatic castration-resistant prostate cancer who were at high risk for the development of metastasis. METHO...

Subject

Prostate cancer

Cancer

Metastasis

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