<i>DICER1</i> and Associated Conditions: Identification of At-risk Individuals and Recommended Surveillance Strategies

Ann P. Schultz, Kris; M. Williams, Gretchen; Kamihara, Junne; R. Stewart, Douglas; K. Harris, Anne; J. Bauer, Andrew; Turner, Joyce; Shah, Rachana; A. Schneider, Katherine; Wolfe Schneider, Kami; G. Carr, Ann; A. Harney, Laura; Baldinger, Shari; Lindsay Frazier, A.; Orbach, Daniel; T. Schneider, Dominik; Malkin, David; P. Dehner, Louis; H. Messinger, Yoav; Ashley Hill, D.

doi:10.1158/1078-0432.ccr-17-3089

Public

DICER1 and Associated Conditions: Identification of At-risk Individuals and Recommended Surveillance Strategies

Published in Clinical Cancer Research • Jan 17, 2018

Authors:

Kris Ann P. Schultz

Gretchen M. Williams

Junne Kamihara

Abstract

Abstract Pathogenic germline DICER1 variants cause a hereditary cancer predisposition syndrome with a variety of manifestations. In addition to conferring increased cancer risks for pleuropulmonary blastoma (PPB) and ovarian sex cord–stromal tumors, particularly Sertoli–Leydig cell tumor, individual...

Subject

Identification (biology)

Environmental health

Medicine

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!