Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice

Brown, M.; P. Assen, F.; Leithner, A.; Abe, J.; Schachner, H.; Asfour, G.; Bago-Horvath, Z.; V. Stein, J.; Uhrin, P.; Sixt, M.; Kerjaschki, D.

doi:10.1126/science.aal3662

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Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice

Shared by NobleBlocks on Mar 23, 2018 • 12:00 AM UTC

Authors:

M. Brown

F. P. Assen

A. Leithner

Abstract

An alternate route for metastatic cells Metastatic tumor cells are thought to reach distant organs by traveling through the blood circulation or the lymphatic system. Two studies of mouse models now suggest a hybrid route for tumor cell dissemination. Pereira et al. and Brown et al. used distinct me...

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