Effect of Haloperidol on Survival Among Critically Ill Adults With a High Risk of Delirium: The REDUCE Randomized Clinical Trial.

den Boogaard M, van; AJC, Slooter; RJM, Brüggemann; L, Schoonhoven; A, Beishuizen; JW, Vermeijden; D, Pretorius; Koning J, de; KS, Simons; PJW, Dennesen; der Voort PHJ, Van; S, Houterman; der Hoeven JG, van; P, Pickkers; der Woude, van; A, Besselink; LS, Hofstra; PE, Spronk; den Bergh W, van; DW, Donker; M, Fuchs; A, Karakus; M, Koeman; Duijnhoven M, van; G, Hannink

doi:10.1001/jama.2018.0160

Public

Effect of Haloperidol on Survival Among Critically Ill Adults With a High Risk of Delirium: The REDUCE Randomized Clinical Trial.

Shared by NobleBlocks on Feb 1, 2018 • 12:00 AM UTC

Authors:

van den Boogaard M

Slooter AJC

Brüggemann RJM

Abstract

Importance Results of studies on use of prophylactic haloperidol in critically ill adults are inconclusive, especially in patients at high risk of delirium.Objective To determine whether prophylactic use of haloperidol improves survival among critically ill adults at high risk of delirium, which was...

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