Switching Reference Medicines to Biosimilars: A Systematic Literature Review of Clinical Outcomes

P. Cohen, Hillel; Blauvelt, Andrew; M. Rifkin, Robert; Danese, Silvio; B. Gokhale, Sameer; R. Woollett, Gillian

doi:10.1007/s40265-018-0881-y

Public

Switching Reference Medicines to Biosimilars: A Systematic Literature Review of Clinical Outcomes

Published in Drugs • Mar 1, 2018

Authors:

Hillel P. Cohen

Andrew Blauvelt

Robert M. Rifkin

Abstract

INTRODUCTION: To evaluate the possibility that switching from reference biologic medicines to biosimilars could lead to altered clinical outcomes, including enhanced immunogenicity, compromised safety, or diminished efficacy for patients, a systematic literature review was conducted of all switching...

Subject

Biosimilar

Medicine

Immunogenicity

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