Transcriptional orchestration of mitochondrial homeostasis in a cellular model of PGC-1-related coactivator-dependent thyroid tumor.

S, Dumont; Pennec S, Le; A, Donnart; R, Teusan; M, Steenman; C, Chevalier; R, Houlgatte; F, Savagner

doi:10.18632/oncotarget.24633

Public

Transcriptional orchestration of mitochondrial homeostasis in a cellular model of PGC-1-related coactivator-dependent thyroid tumor.

Shared by NobleBlocks on Mar 23, 2018 • 12:00 AM UTC

Authors:

Dumont S

Le Pennec S

Donnart A

Abstract

The PGC-1 (Peroxisome proliferator-activated receptor Gamma Coactivator-1) family of coactivators (PGC-1α, PGC-1β, and PRC) plays a central role in the transcriptional control of mitochondrial biogenesis and oxidative phosphorylation (OXPHOS) processes. These coactivators integrate mitochondrial ene...

Subject

Transcription factors

miRNAs

Pgc-1-related Coactivator

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