RAS mutation analysis in circulating tumor DNA from patients with metastatic colorectal cancer: the AGEO RASANC prospective multicenter study

Bachet, Jean‐Baptiste; Bouché, Olivier; Taı̈eb, Julien; Dubreuil, Olivier; Luisa García, M.; Meurisse, Aurélia; Normand, C.; Gornet, J.M.; Artru, Pascal; Louafi, Samy; Bonnetain, Franck; Thirot‐Bidault, Anne; Baumgaertner, Isabelle; Coriat, Romain; Tougeron, David; Lecomte, Thierry; Mary, Florence; Aparicio, Thomas; Marthey, Lysiane; Taly, Valérie; Blons, Hélène; Vernerey, Déwi; Laurent‐Puig, Pierre

doi:10.1093/annonc/mdy061

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RAS mutation analysis in circulating tumor DNA from patients with metastatic colorectal cancer: the AGEO RASANC prospective multicenter study

Published in Annals of Oncology • Feb 9, 2018

Authors:

Jean‐Baptiste Bachet

Olivier Bouché

Julien Taı̈eb

Abstract

Background: RAS mutations are currently sought for in tumor samples, which takes a median of almost 3 weeks in western European countries. This creates problems in clinical situations that require urgent treatment and for inclusion in therapeutic trials that need RAS status for randomization. Analys...

Subject

Medicine

Colorectal cancer

Circulating tumor DNA

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