Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques

Guedj, Jérémie; Piorkowski, Géraldine; Jacquot, Frédéric; Madelain, Vincent; Huyen Tram Nguyen, Thi; Rodallec, Anne; Günther, Stephan; Carbonnelle, Caroline; Mentré, France; Raoul, Hervé; de Lamballerie, Xavier

doi:10.1371/journal.pmed.1002535

Public

Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques

Published in PLoS Medicine • Mar 27, 2018

Authors:

Jérémie Guedj

Géraldine Piorkowski

Frédéric Jacquot

Abstract

BACKGROUND: Despite repeated outbreaks, in particular the devastating 2014-2016 epidemic, there is no effective treatment validated for patients with Ebola virus disease (EVD). Among the drug candidates is the broad-spectrum polymerase inhibitor favipiravir, which showed a good tolerance profile in ...

Subject

Favipiravir

Ebola virus

Virology

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