A Vaccine Platform against Arenaviruses Based on a Recombinant Hyperattenuated Mopeia Virus Expressing Heterologous Glycoproteins

Carnec, Xavier; Mateo, Mathieu; Page, Audrey; Reynard, Stéphanie; Hortion, Jimmy; Picard, Caroline; Laban Yekwa, Elsie; Barrot, Laura; Barron, Stéphane; Vallvé, Audrey; Raoul, Hervé; Carbonnelle, Caroline; Ferrón, François; Baize, Sylvain

doi:10.1128/jvi.02230-17

Public

A Vaccine Platform against Arenaviruses Based on a Recombinant Hyperattenuated Mopeia Virus Expressing Heterologous Glycoproteins

Published in Journal of Virology • Mar 28, 2018

Authors:

Xavier Carnec

Mathieu Mateo

Audrey Page

Abstract

ABSTRACT Several Old World and New World arenaviruses are responsible for severe endemic and epidemic hemorrhagic fevers, whereas other members of the Arenaviridae family are nonpathogenic. To date, no approved vaccines, antivirals, or specific treatments are available, except for Junín virus. Howev...

Subject

Biology

Virology

Heterologous

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