EBNA1: Oncogenic Activity, Immune Evasion and Biochemical Functions Provide Targets for Novel Therapeutic Strategies against Epstein-Barr Virus- Associated Cancers

B. Wilson, Joanna; Manet, Évelyne; Gruffat, Henri; Busson, Pierre; Blondel, Marc; Fåhræus, Robin

doi:10.3390/cancers10040109

Public

EBNA1: Oncogenic Activity, Immune Evasion and Biochemical Functions Provide Targets for Novel Therapeutic Strategies against Epstein-Barr Virus- Associated Cancers

Published in Cancers • Apr 6, 2018

Authors:

Joanna B. Wilson

Évelyne Manet

Henri Gruffat

Abstract

The presence of the Epstein-Barr virus (EBV)-encoded nuclear antigen-1 (EBNA1) protein in all EBV-carrying tumours constitutes a marker that distinguishes the virus-associated cancer cells from normal cells and thereby offers opportunities for targeted therapeutic intervention. EBNA1 is essential fo...

Subject

Virus

Biology

Immune system

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!