RETRACTED ARTICLE: Targeted production of reactive oxygen species in mitochondria to overcome cancer drug resistance

Wang, Hai; Gao, Zan; Liu, Xuanyou; Agarwal, Pranay; Zhao, Shuting; W. Conroy, Daniel; Ji, Guang; Yu, Jianhua; P. Jaroniec, Christopher; Liu, Zhenguo; Lu, Xiongbin; Li, Xiaodong; He, Xiaoming

doi:10.1038/s41467-018-02915-8

Public

RETRACTED ARTICLE: Targeted production of reactive oxygen species in mitochondria to overcome cancer drug resistance

Published in Nature Communications • Feb 2, 2018

Authors:

Hai Wang

Zan Gao

Xuanyou Liu

Abstract

Abstract Multidrug resistance is a major challenge to cancer chemotherapy. The multidrug resistance phenotype is associated with the overexpression of the adenosine triphosphate (ATP)-driven transmembrane efflux pumps in cancer cells. Here, we report a lipid membrane-coated silica-carbon (LSC) hybri...

Subject

Efflux

Multiple drug resistance

Reactive oxygen species

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