Parallel derivation of isogenic human primed and naive induced pluripotent stem cells

Kilens, Stéphanie; Meistermann, Dimitri; Moreno, Diego; Chariau, Caroline; Gaignerie, Anne; Reignier, Arnaud; Lelièvre, Yohann; Casanova, Miguel; Vallot, Céline; Nédellec, Steven; Flippe, Léa; Firmin, Julie; Song, Juan; Charpentier, Éric; Lammers, Jenna; Donnart, Audrey; Marec, Nadège; Deb, Wallid; Bihouée, Audrey; Le Caignec, Cédric; Pecqueur, Claire; Redon, Richard; Barrière, P.; Bourdon, Jérémie; Pasque, Vincent; Soumillon, Magali; S. Mikkelsen, Tarjei; Rougeulle, Claire; Fréour, Thomas; David, Laurent; Abel, Laurent; Alcover, Andrés; Astrom, Kalla; Bousso, Philippe; Bruhns, Pierre; Cumano, Ana; Duffy, Darragh; Demangel, Caroline; Deriano, Ludovic; P. Di Santo, James; Dromer, Françoise; Eberl, Gérard; Enninga, Jost; Fellay, Jacques; A. Freitas, António; Gelpi, Odile; Gomperts-Boneca, Ivo; Hercberg, Serge; Lantz, Olivier; Leclerc, Claude; Mouquet, Hugo; Patin, Étienne; Pellegrini, Sandra; Pol, Stanislas; Rogge, Lars; Sakuntabhai, Anavaj; Schwartz, Olivier; Schwikowski, Benno; Shorte, Spencer; Soumelis, Vassili; Tangy, Frédéric; Tartour, Éric; Toubert, Antoine; Ungeheuer, Marie-Noëlle; Quintana‐Murci, Lluís; L. Albert, Matthew

doi:10.1038/s41467-017-02107-w

Public

Parallel derivation of isogenic human primed and naive induced pluripotent stem cells

Published in Nature Communications • Jan 18, 2018

Authors:

Stéphanie Kilens

Dimitri Meistermann

Diego Moreno

Abstract

Induced pluripotent stem cells (iPSCs) have considerably impacted human developmental biology and regenerative medicine, notably because they circumvent the use of cells of embryonic origin and offer the potential to generate patient-specific pluripotent stem cells. However, conventional reprogrammi...

Subject

Epiblast

Induced pluripotent stem cell

Reprogramming

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