Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma

Schmitz, Roland; W. Wright, George; Wei Huang, Da; A. Johnson, Calvin; D. Phelan, James; Q. Wang, James; Roulland, Sandrine; Kasbekar, Monica; M. Young, Ryan; L. Shaffer, Arthur; J. Hodson, Daniel; Xiao, Wenming; Yu, Xin; Yang, Yandan; Zhao, Hong; Xu, Weihong; Liu, Xuelu; Zhou, Bin; Du, Wei; C. Chan, Wing; S. Jaffe, Elaine; D. Gascoyne, Randy; M. Connors, Joseph; Campo, Elı́as; López‐Guillermo, Armando; Rosenwald, Andreas; Ott, German; Delabie, Jan; M. Rimsza, Lisa; Tay Kuang Wei, Kevin; D. Zelenetz, Andrew; P. Leonard, John; L. Bartlett, Nancy; Tran, Bao; Shetty, Jyoti; Zhao, Yongmei; Soppet, Dan; Pittaluga, Stefania; H. Wilson, Wyndham; M. Staudt, Louis

doi:10.1056/nejmoa1801445

Public

Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma

Published in New England Journal of Medicine • Apr 11, 2018

Authors:

Roland Schmitz

George W. Wright

Da Wei Huang

Abstract

BACKGROUND: Diffuse large B-cell lymphomas (DLBCLs) are phenotypically and genetically heterogeneous. Gene-expression profiling has identified subgroups of DLBCL (activated B-cell-like [ABC], germinal-center B-cell-like [GCB], and unclassified) according to cell of origin that are associated with a ...

Subject

Biology

Germinal center

Diffuse large B-cell lymphoma

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