Measuring multiple parameters of CD8+ tumor-infiltrating lymphocytes in human cancers by image analysis.

KE, Steele; TH, Tan; R, Korn; K, Dacosta; C, Brown; M, Kuziora; J, Zimmermann; B, Laffin; M, Widmaier; L, Rognoni; R, Cardenes; K, Schneider; A, Boutrin; P, Martin; J, Zha; T, Wiestler

doi:10.1186/s40425-018-0326-x

Public

Measuring multiple parameters of CD8+ tumor-infiltrating lymphocytes in human cancers by image analysis.

Shared by NobleBlocks on Mar 6, 2018 • 12:00 AM UTC

Authors:

Steele KE

Tan TH

Korn R

Abstract

Background Immuno-oncology and cancer immunotherapies are areas of intense research. The numbers and locations of CD8+ tumor-infiltrating lymphocytes (TILs) are important measures of the immune response to cancer with prognostic, pharmacodynamic, and predictive potential. We describe the development...

Subject

Image analysis

CD8

Cancer Immunotherapy

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