Enhanced Levels and Enhanced Clonogenic Capacity of Blood Progenitor Cells Following Administration of Stem Cell Factor Plus Granulocyte Colony-Stimulating Factor to Humans

Glenn Begley, C.; Basser, R.; Mansfield, Rachel; J. Thomson, Brian; Rushton Parker, William; E. Layton, Judith; To, Bik; Cebon, Jonathan; Sheridan, William; M. Fox, R.; Green, M.D.

doi:10.1182/blood.v90.9.3378

Public

Enhanced Levels and Enhanced Clonogenic Capacity of Blood Progenitor Cells Following Administration of Stem Cell Factor Plus Granulocyte Colony-Stimulating Factor to Humans

Published in Blood • Nov 1, 1997

Authors:

C. Glenn Begley

R. Basser

Rachel Mansfield

Abstract

Administration of hematopoietic growth factors is being used increasingly to obtain populations of blood progenitor/stem cells (PBPC) for clinical transplantation. Here we examined the effect of combining stem cell factor (SCF ) and granulocyte colony-stimulating factor (G-CSF ) versus G-CSF alone i...

Subject

Granulocyte colony-stimulating factor

Stem cell factor

Medicine

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