Increased Iron Deposition on Brain Quantitative Susceptibility Mapping Correlates with Decreased Cognitive Function in Alzheimer's Disease.

L, Du; Z, Zhao; A, Cui; Y, Zhu; L, Zhang; J, Liu; S, Shi; C, Fu; X, Han; W, Gao; T, Song; L, Xie; L, Wang; S, Sun; R, Guo; G, Ma

doi:10.1021/acschemneuro.8b00194

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Increased Iron Deposition on Brain Quantitative Susceptibility Mapping Correlates with Decreased Cognitive Function in Alzheimer's Disease.

Shared by NobleBlocks on May 15, 2018 • 12:00 AM UTC

Authors:

Du L

Zhao Z

Cui A

Abstract

The excessive accumulation of iron in deep gray structures is an important pathological characteristic in patients with Alzheimer's disease (AD). Quantitative susceptibility mapping (QSM) is more specific than other imaging-based iron measurement modalities and allows noninvasive assessment of tissu...

Subject

Cognitive function

Alzheimer’s disease

Mini-mental State Examination

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