Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

Demontis, Ditte; K. Walters, Raymond; Martin, Joanna; Mattheisen, Manuel; D. Als, Thomas; Agerbo, Esben; Baldursson, Gísli; Belliveau, Rich; Bybjerg‐Grauholm, Jonas; Bækvad‐Hansen, Marie; Cerrato, Felecia; Chambert, Kimberly; Churchhouse, Claire; Dumont, Ashley; Eriksson, Nicholas; J. Gandal, Michael; I. Goldstein, Jacqueline; L. Grasby, Katrina; Grove, Jakob; Ó. Guðmundsson, Ólafur; Søholm Hansen, Christine; E. Hauberg, Mads; V. Hollegaard, Mads; P. Howrigan, Daniel; Huang, Hailiang; Maller, Julian; R. Martin, Alicia; G. Martin, Nicholas; L. Moran, Jennifer; Pallesen, Jonatan; S. Palmer, Duncan; Bøcker Pedersen, Carsten; Giørtz Pedersen, Marianne; Poterba, Timothy; Buchhave Poulsen, Jesper; Ripke, Stephan; Robinson, Elise; Kyle Satterstrom, F.; Stefánsson, Hreinn; Stevens, Christine; Turley, Patrick; Bragi Walters, G.; Won, Hyejung; J. Wright, Margaret; A. Andreassen, Ole; Asherson, Philip; L. Burton, Christie; I. Boomsma, Dorret; Cormand, Bru; Dalsgaard, Søren; Franke, Barbara; Gelernter, Joel; H. Geschwind, Daniel; Håkonarson, Håkon; Haavik, Jan; R. Kranzler, Henry; Kuntsi, Jonna; Langley, K.; Lesch, Klaus‐Peter; M. Middeldorp, Christel; Reif, Andreas; Augusto Rohde, Luís; Roussos, Panos; Schachar, Russell; Sklar, Pamela; Sonuga‐Barke, Edmund; F. Sullivan, Patrick; Thapar, Anita; Y. Tung, Joyce; D. Waldman, Irwin; E. Medland, Sarah; Stefánsson, Kāri; Nordentoft, Merete; M. Hougaard, David; Werge, Thomas; Mors, Ole; Bo Mortensen, Preben; J. Daly, Mark; V. Faraone, Stephen; D. Børglum, Anders; M. Neale, Benjamin

doi:10.1038/s41588-018-0269-7

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Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

Published in Nature Genetics • Nov 23, 2018

Authors:

Ditte Demontis

Raymond K. Walters

Joanna Martin

Abstract

Attention deficit/hyperactivity disorder (ADHD) is a highly heritable childhood behavioral disorder affecting 5% of children and 2.5% of adults. Common genetic variants contribute substantially to ADHD susceptibility, but no variants have been robustly associated with ADHD. We report a genome-wide a...

Subject

Biology

Attention deficit hyperactivity disorder

Genome-wide association study

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