Rituximab for auto-immune alveolar proteinosis, a real life cohort study

Soyez, B.; Borie, Raphaël; Menard, Cédric; Cadranel, Jacques; Chavez, Leonidas; Cottin, Vincent; Gomez, E.; Marchand‐Adam, S.; Leroy, Sylvie; Naccache, Jean‐Marc; Nunès, Hilario; Reynaud‐Gaubert, Martine; Savale, Laurent; Tazi, Abdellatif; Wémeau-Stervinou, Lidwine; Debray, Marie‐Pierre; Crestani, Bruno

doi:10.1186/s12931-018-0780-5

Public

Rituximab for auto-immune alveolar proteinosis, a real life cohort study

Published in Respiratory Research • Apr 25, 2018

Authors:

B. Soyez

Raphaël Borie

Cédric Menard

Abstract

BACKGROUND: Whole lung lavage is the current standard therapy for pulmonary alveolar proteinosis (PAP) that is characterized by the alveolar accumulation of surfactant. Rituximab showed promising results in auto-immune PAP (aPAP) related to anti-GM-CSF antibody. METHODS: We aimed to assess efficacy ...

Subject

Medicine

Rituximab

Refractory (planetary science)

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