Genetic Etiology for Alcohol-Induced Cardiac Toxicity

S. Ware, James; Amor‐Salamanca, Almudena; Tayal, Upasana; Govind, Risha; Serrano, Isabel; Salazar‐Mendiguchía, Joel; Manuel García‐Pinilla, José; A. Pascual‐Figal, Domingo; Núñez, Julio; Guzzo-Merello, Gonzalo; González‐Vioque, Emiliano; Bardajı́, Alfredo; Manito, Nicolás; A. López-Garrido, Miguel; Padrón-Barthe, Laura; Edwards, Elizabeth; Whiffin, Nicola; Walsh, Roddy; Buchan, Rachel; Midwinter, William; Wilk, Alicja; Prasad, Sanjay; Pantazis, Antonis; Baski, John; P. O’Regan, Declan; Alonso‐Pulpón, Luis; A. Cook, Stuart; Lara‐Pezzi, Enrique; J.R. Barton, Paul; García‐Pavía, Pablo

doi:10.1016/j.jacc.2018.03.462

Public

Genetic Etiology for Alcohol-Induced Cardiac Toxicity

Published in Journal of the American College of Cardiology • May 1, 2018

Authors:

James S. Ware

Almudena Amor‐Salamanca

Upasana Tayal

Abstract

BACKGROUND: Alcoholic cardiomyopathy (ACM) is defined by a dilated and impaired left ventricle due to chronic excess alcohol consumption. It is largely unknown which factors determine cardiac toxicity on exposure to alcohol. OBJECTIVES: This study sought to evaluate the role of variation in cardiomy...

Subject

Medicine

Alcoholic cardiomyopathy

Dilated cardiomyopathy

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