The synergistic effects of saxagliptin and metformin on CD34+ endothelial progenitor cells in early type 2 diabetes patients: a randomized clinical trial

J. Dore, Fiona; C. Domingues, Cleyton; Ahmadi, Neeki; Kundu, Nabanita; Kropotova, Yana; Houston, Sara; Rouphael, Carol; Mammadova, Aytan; Witkin, Linda; Khiyami, Anamil; Amdur, Richard; Sen, Sabyasachi

doi:10.1186/s12933-018-0709-9

Public

The synergistic effects of saxagliptin and metformin on CD34+ endothelial progenitor cells in early type 2 diabetes patients: a randomized clinical trial

Published in Cardiovascular Diabetology • May 3, 2018

Authors:

Fiona J. Dore

Cleyton C. Domingues

Neeki Ahmadi

Abstract

AIMS: Type 2 diabetes is associated with endothelial dysfunction leading to cardiovascular disease. CD34+ endothelial Progenitor Cells (EPCs) are responsible for endothelial repair and neo-angiogenesis and can be used as a cardiovascular disease risk biomarker. This study investigated whether the ad...

Subject

Saxagliptin

Medicine

Metformin

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