Sunitinib Alone or after Nephrectomy in Metastatic Renal-Cell Carcinoma

Méjean, Arnaud; Ravaud, Alain; Thézenas, Simon; Colas, Sandra; Beauval, Jean‐Baptiste; Bensalah, Karim; Geoffrois, Lionnel; Thiery-Vuillemin, Antoine; Cormier, Luc; Lang, Hervé; Guy, Laurent; Gravis, Gwénaëlle; Rolland, Frédéric; Linassier, Claude; Lechevallier, É.; Beisland, Christian; Aitchison, Michael; Oudard, Stéphane; Patard, Jean‐Jacques; Théodore, C; Chevreau, Christine; Laguerre, Brigitte; Hubert, Jacques; Gross‐Goupil, Marine; Bernhard, Jean‐Christophe; Albigès, Laurence; Timsit, Marc‐Olivier; Lebrét, Thierry; Escudier, Bernard

doi:10.1056/nejmoa1803675

Public

Sunitinib Alone or after Nephrectomy in Metastatic Renal-Cell Carcinoma

Published in New England Journal of Medicine • Jun 3, 2018

Authors:

Arnaud Méjean

Alain Ravaud

Simon Thézenas

Abstract

BACKGROUND: Cytoreductive nephrectomy has been the standard of care in metastatic renal-cell carcinoma for 20 years, supported by randomized trials and large, retrospective studies. However, the efficacy of targeted therapies has challenged this standard. We assessed the role of nephrectomy in patie...

Subject

Sunitinib

Renal cell carcinoma

Nephrectomy

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