Carbamoylated erythropoietin modulates cognitive outcomes of social defeat and differentially regulates gene expression in the dorsal and ventral hippocampus

Sathyanesan, Monica; J. Watt, Michael; M. Haiar, Jacob; L. Scholl, Jamie; R. Davies, Shaydel; T. Paulsen, Riley; Wiederin, Jayme; Ciborowski, Paweł; S. Newton, Samuel

doi:10.1038/s41398-018-0168-9

Public

Carbamoylated erythropoietin modulates cognitive outcomes of social defeat and differentially regulates gene expression in the dorsal and ventral hippocampus

Published in Translational Psychiatry • Jun 8, 2018

Authors:

Monica Sathyanesan

Michael J. Watt

Jacob M. Haiar

Abstract

Cognitive deficits are widespread in psychiatric disorders and frequently as debilitating as the affective component. Widely prescribed antidepressants for treating depressive disorders have limited efficacy in normalizing cognitive function. Erythropoietin (Epo) has been shown to improve cognitive ...

Subject

Erythropoietin

Hippocampus

Medicine

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