Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells in Macular Degeneration

Mehat, Manjit; Sundaram, Venki; Ripamonti, Caterina; G. Robson, Anthony; J. Smith, Alexander; Borooah, Shyamanga; R. Robinson, Martha; N. Rosenthal, Adam; A. Innes, William; G. Weleber, Richard; Lee, Richard; D. Crossland, Michael; S. Rubin, Gary; Dhillon, Baljean; Steel, David; Anglade, Eddy; Lanza, Robert; R. Ali, Robin; Michaelides, Michel; Bainbridge, James

doi:10.1016/j.ophtha.2018.04.037

Public

Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells in Macular Degeneration

Published in Ophthalmology • Jun 5, 2018

Authors:

Manjit Mehat

Venki Sundaram

Caterina Ripamonti

Abstract

PURPOSE: Transplantation of human embryonic stem cell (hESC)-derived retinal pigment epithelial (RPE) cells offers the potential for benefit in macular degeneration. Previous trials have reported improved visual acuity (VA), but lacked detailed analysis of retinal structure and function in the treat...

Subject

Embryonic stem cell

Medicine

Macular degeneration

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