Candida Infections and Therapeutic Strategies: Mechanisms of Action for Traditional and Alternative Agents

Cutrim de Oliveira Santos, Giselle; Costa Vasconcelos, Cleydlenne; Jorge Oliveira Lopes, Alberto; do Socorro de Sousa Cartágenes, Maria; K. D. B. Filho, Allan; Raquel Fernandes do Nascimento, Flávia; Martins Ramos, Ricardo; R. R. B. Pires, Emygdia; Souza de Andrade, Marcelo; Maria Galvão Rocha, Flaviane; de Andrade Monteiro, Cristina

doi:10.3389/fmicb.2018.01351

Public

Candida Infections and Therapeutic Strategies: Mechanisms of Action for Traditional and Alternative Agents

Published in Frontiers in Microbiology • Jul 3, 2018

Authors:

Giselle Cutrim de Oliveira Santos

Cleydlenne Costa Vasconcelos

Alberto Jorge Oliveira Lopes

Abstract

The Candida genus comprises opportunistic fungi that can become pathogenic when the immune system of the host fails. Candida albicans is the most important and prevalent species. Polyenes, fluoropyrimidines, echinocandins, and azoles are used as commercial antifungal agents to treat candidiasis. How...

Subject

Antifungal

Echinocandins

Candida albicans

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