Antiretroviral Drugs Alter the Content of Extracellular Vesicles from HIV-1-Infected Cells

DeMarino, Catherine; L. Pleet, Michelle; Cowen, Maria; A. Barclay, Robert; Akpamagbo, Yao; Erickson, James; Ndembi, Nicaise; Charurat, Manhattan; Jumare, Jibreel; Bwala, Sunday; Alabi, Peter; Hogan, Max; Gupta, Archana; Noren Hooten, Nicole; K. Evans, Michele; Lepene, Benjamin; Zhou, Weidong; Caputi, Massimo; Romerio, Fabio; Royal, Walter; El-Hage, Nazira; A. Liotta, Lance; Kashanchi, Fatah

doi:10.1038/s41598-018-25943-2

Public

Antiretroviral Drugs Alter the Content of Extracellular Vesicles from HIV-1-Infected Cells

Shared by NobleBlocks on May 16, 2018 • 12:00 AM UTC

Authors:

Catherine DeMarino

Michelle L. Pleet

Maria Cowen

Abstract

Abstract To date, the most effective treatment of HIV-1 is a combination antiretroviral therapy (cART), which reduces viral replication and reverses pathology. We investigated the effect of cART (RT and protease inhibitors) on the content of extracellular vesicles (EVs) released from HIV-1-infected ...

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