Immune System Dysregulation During Spaceflight: Potential Countermeasures for Deep Space Exploration Missions

Crucian, Brian; Choukèr, Alexander; J. Simpson, Richard; Mehta, Satish; D. Marshall, Gailen; M. Smith, Scott; R. Zwart, Sara; Heer, Martina; А. Пономарев, С.; Whitmire, Alexandra; P. Frippiat, Jean; L. Douglas, Grace; Lorenzi, Hernán; Buchheim, Judith‐Irina; Makedonas, George; S. Ginsburg, Geoffrey; Mark Ott, C.; L. Pierson, Duane; Krieger, Stephanie; Baecker, Natalie; F. Sams, Clarence

doi:10.3389/fimmu.2018.01437

Public

Immune System Dysregulation During Spaceflight: Potential Countermeasures for Deep Space Exploration Missions

Published in Frontiers in Immunology • Jun 28, 2018

Authors:

Brian Crucian

Alexander Choukèr

Richard J. Simpson

Abstract

Recent studies have established that dysregulation of the human immune system and the reactivation of latent herpesviruses persists for the duration of a 6-month orbital spaceflight. It appears certain aspects of adaptive immunity are dysregulated during flight, yet some aspects of innate immunity a...

Subject

Crew

Spaceflight

Space exploration

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