Identification of Biomarkers for Differentiation of Hypervirulent Klebsiella pneumoniae from Classical K. pneumoniae

A. Russo, Thomas; Olson, Ruth; Fang, Chi‐Tai; Stoesser, Nicole; A. Miller, Mark; MacDonald, Ulrike; D. Hutson, Alan; Barker, Jason; M. La Hoz, Ricardo; R. Johnson, James; Bäcker, Martín; Bajwa, Rajinder; Catanzaro, Andrew; W. Crook, Derrick; de Almeda, Kleper; Fierer, Joshua; E. Greenberg, David; Klevay, Michael; Patel, Payal; J. Ratner, Adam; Wang, Jann‐Tay; Żola, Jarosław

doi:10.1128/jcm.00776-18

Public

Identification of Biomarkers for Differentiation of Hypervirulent Klebsiella pneumoniae from Classical K. pneumoniae

Published in Journal of Clinical Microbiology • Jun 19, 2018

Authors:

Thomas A. Russo

Ruth Olson

Chi‐Tai Fang

Abstract

were all associated with a hazard ratio of >25 for severe illness or death, additionally supporting their utility for identifying hvKp strains. Quantitative siderophore production of ≥30 μg/ml also strongly predicted strains as members of the hvKp-rich cohort (accuracy, 0.96) and exhibited a hazard ...

Subject

Klebsiella pneumoniae

Microbiology

Klebsiella infections

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