Medication-related osteonecrosis of the jaw: Prevention, diagnosis and management in patients with cancer and bone metastases

Otto, Sven; Pautke, Christoph; Van den Wyngaert, Tim; Niepel, Daniela; Schiødt, Morten

doi:10.1016/j.ctrv.2018.06.007

Public

Medication-related osteonecrosis of the jaw: Prevention, diagnosis and management in patients with cancer and bone metastases

Published in Cancer Treatment Reviews • Jun 18, 2018

Authors:

Sven Otto

Christoph Pautke

Tim Van den Wyngaert

Abstract

Medication-related osteonecrosis of the jaw (MRONJ) is primarily an adverse side effect of denosumab or bisphosphonates (particularly when used at high doses to prevent skeletal-related events [SREs] in patients with cancer and bone metastases) or possibly anti-angiogenic cancer treatment. While the...

Subject

Medicine

Osteonecrosis of the jaw

Jaw bone

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