Multidimensional analyses reveal distinct immune microenvironment in hepatitis B virus-related hepatocellular carcinoma

Jye Lim, Chun; Hua Lee, Yun; Pan, Lu; Lai, Liyun; Chua, Camillus; Wasser, Martin; Kiat Hon Lim, Tony; Yeong, Joe; Chong Toh, Han; Yee Lee, Ser; Yip Chan, Chung; K. P. Goh, Brian; Chung, Alexander; Heikenwälder, Mathias; Oi‐Lin Ng, Irene; K. H. Chow, Pierce; Albani, Salvatore; Chew, Valerie

doi:10.1136/gutjnl-2018-316510

Public

Multidimensional analyses reveal distinct immune microenvironment in hepatitis B virus-related hepatocellular carcinoma

Published in Gut • Jul 3, 2018

Authors:

Chun Jye Lim

Yun Hua Lee

Lu Pan

Abstract

Background and aims Chronic inflammation induced by chronic hepatitis B virus (HBV) infection increases the risk of hepatocellular carcinoma (HCC). However, little is known about the immune landscape of HBV-related HCC and its influence on the design of effective cancer immunotherapeutics. Methods W...

Subject

Hepatocellular carcinoma

Hepatitis B virus

Immune system

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