Identification of novel diabetes impaired miRNA-transcription factor co-regulatory networks in bone marrow-derived Lin-/VEGF-R2+ endothelial progenitor cells

R. Irhimeh, Mohammad; Hamed, Mohamed; Barthelmes, Daniel; Saara Gladbach, Yvonne; Helms, Volkhard; Shen, Weiyong; C. Gillies, Mark

doi:10.1371/journal.pone.0200194

Public

Identification of novel diabetes impaired miRNA-transcription factor co-regulatory networks in bone marrow-derived Lin-/VEGF-R2+ endothelial progenitor cells

Published in PLoS ONE • Jul 11, 2018

Authors:

Mohammad R. Irhimeh

Mohamed Hamed

Daniel Barthelmes

Abstract

Endothelial progenitor cells (EPCs) are a group of rare cells that play an important role in the repair of injured vascular endothelial cells and assist in reperfusion of ischemic tissue. Decreased production and/or loss of function of EPCs are associated with diabetic vasculopathy. The molecular me...

Subject

Progenitor cell

Bone marrow

microRNA

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