Design and fabrication of a liver-on-a-chip platform for convenient, highly efficient, and safe <i>in situ</i> perfusion culture of 3D hepatic spheroids

Ma, Li-Dong; Wang, Yitong; Wang, Jingrong; Wu, Jian‐Lin; Meng, Xiansheng; Hu, Ping; Mu, Xuan; Liang, Qionglin; Luo, Guoan

doi:10.1039/c8lc00333e

Public

Design and fabrication of a liver-on-a-chip platform for convenient, highly efficient, and safe in situ perfusion culture of 3D hepatic spheroids

Published in Lab on a Chip • Jan 1, 2018

Authors:

Li-Dong Ma

Yitong Wang

Jingrong Wang

Abstract

Spheroid-based three-dimensional (3D) liver culture models, offering a desirable biomimetic microenvironment, are useful for recapitulating liver functions in vitro. However, a user-friendly, robust and specially optimized method has not been well developed for a convenient, highly efficient, and sa...

Subject

Spheroid

In situ

Fabrication

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