Effect of Alteplase vs Aspirin on Functional Outcome for Patients With Acute Ischemic Stroke and Minor Nondisabling Neurologic Deficits

Khatri, Pooja; Kleindorfer, Dawn; Devlin, Thomas; N. Sawyer, Robert; Starr, Matthew; Mejilla, Jennifer; P. Broderick, Joseph; Chatterjee, Anjan; C. Jauch, Edward; R. Levine, Steven; G. Romano, José; L. Saver, Jeffrey; Vagal, Achala; Purdon, Barbara; Devenport, Jenny; Pavlov, Andrey; D. Yeatts, Sharon; the PRISMS Investigators, for

doi:10.1001/jama.2018.8496

Public

Effect of Alteplase vs Aspirin on Functional Outcome for Patients With Acute Ischemic Stroke and Minor Nondisabling Neurologic Deficits

Published in JAMA • Jul 10, 2018

Authors:

Pooja Khatri

Dawn Kleindorfer

Thomas Devlin

Abstract

Importance: More than half of patients with acute ischemic stroke have minor neurologic deficits (National Institutes of Health Stroke Scale [NIHSS] score of 0-5) at presentation. Although prior major trials of alteplase included patients with low NIHSS scores, few without clearly disabling deficits...

Subject

Medicine

Aspirin

Stroke (engine)

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