Single-cell RNA-seq analysis reveals the progression of human osteoarthritis

Ji, Quanbo; Zheng, Yuxuan; Zhang, Guoqiang; Hu, Yuqiong; Fan, Xiaoying; Hou, Yu; Wen, Lu; Li, Li; Xu, Yameng; Wang, Yan; Tang, Fuchou

doi:10.1136/annrheumdis-2017-212863

Public

Single-cell RNA-seq analysis reveals the progression of human osteoarthritis

Published in Annals of the Rheumatic Diseases • Jul 19, 2018

Authors:

Quanbo Ji

Yuxuan Zheng

Guoqiang Zhang

Abstract

OBJECTIVES: Understanding the molecular mechanisms underlying human cartilage degeneration and regeneration is helpful for improving therapeutic strategies for treating osteoarthritis (OA). Here, we report the molecular programmes and lineage progression patterns controlling human OA pathogenesis us...

Subject

Osteoarthritis

Cartilage

Transcriptome

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