Therapeutic and prophylactic gastrectomy in a family with hereditary diffuse gastric cancer secondary to a CDH1 mutation: a case series

Gjyshi, Olsi; G. Vashi, Pankaj; Seewald, Laura; Kohan, Mitra; Abboud, Elham; S. Fowler, Eric; Suppiah, Revathi; M. El Halabi, Hatem

doi:10.1186/s12957-018-1415-5

Public

Therapeutic and prophylactic gastrectomy in a family with hereditary diffuse gastric cancer secondary to a CDH1 mutation: a case series

Published in World Journal of Surgical Oncology • Jul 14, 2018

Authors:

Olsi Gjyshi

Pankaj G. Vashi

Laura Seewald

Abstract

BACKGROUND: Gastric cancer is the fifth most prevalent and the third most lethal cancer worldwide, causing approximately 720,000 deaths annually. Although most cases of gastric cancers are sporadic, one of its inherited forms, hereditary diffuse gastric cancer (HDGC), constitutes about 1-3% of cases...

Subject

Medicine

Cancer

Surgical oncology

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