Lactobacillus sakei WIKIM30 Ameliorates Atopic Dermatitis-Like Skin Lesions by Inducing Regulatory T Cells and Altering Gut Microbiota Structure in Mice

Kwon, Min-Sung; Ki Lim, Seul; Jang, Ja-Young; Lee, Ji‐Eun; Kyeong Park, Hyo; Kim, Namhee; Yun, Misun; Shin, Mi-Young; Eun Jo, Hee; J. Oh, Young; Woon Roh, Seong; Choi, Hak-Jong

doi:10.3389/fimmu.2018.01905

Public

Lactobacillus sakei WIKIM30 Ameliorates Atopic Dermatitis-Like Skin Lesions by Inducing Regulatory T Cells and Altering Gut Microbiota Structure in Mice

Published in Frontiers in Immunology • Aug 14, 2018

Authors:

Min-Sung Kwon

Seul Ki Lim

Ja-Young Jang

Abstract

Lactobacillus sakei WIKIM30 is a Gram-positive facultative anaerobic bacterium isolated from kimchi, a Korean fermented vegetable food. In this study, we found that WIKIM30 promoted regulatory T cell (Treg) differentiation by inducing dendritic cells with tolerogenic properties. The production of th...

Subject

Immunology

Mesenteric lymph nodes

Atopic dermatitis

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