RETRACTED: Sargassum serratifolium Extract Attenuates Interleukin-1β-Induced Oxidative Stress and Inflammatory Response in Chondrocytes by Suppressing the Activation of NF-κB, p38 MAPK, and PI3K/Akt

Park, Cheol; Jeong, Jin-Woo; Lee, Dae-Sung; Yim, Mi‐Jin; Min Lee, Jeong; Ho Han, Min; Kim, Suhkmann; Kim, Heui‐Soo; Kim, Gi‐Young; Kyun Park, Eui; Jeon, You‐Jin; Cha, Hee‐Jae; Hyun Choi, Yung

doi:10.3390/ijms19082308

Public

RETRACTED: Sargassum serratifolium Extract Attenuates Interleukin-1β-Induced Oxidative Stress and Inflammatory Response in Chondrocytes by Suppressing the Activation of NF-κB, p38 MAPK, and PI3K/Akt

Published in International Journal of Molecular Sciences • Aug 7, 2018

Authors:

Cheol Park

Jin-Woo Jeong

Dae-Sung Lee

Abstract

Osteoarthritis (OA) is a degenerative joint disease that is characterized by irreversible articular cartilage destruction by inflammatory reaction. Among inflammatory stimuli, interleukin-1β (IL-1β) is known to play a crucial role in OA pathogenesis by stimulating several mediators that contribute t...

Subject

p38 mitogen-activated protein kinases

PI3K/AKT/mTOR pathway

Protein kinase B

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