Prognostic value of interferon-γ release assays and tuberculin skin test in predicting the development of active tuberculosis (UK PREDICT TB): a prospective cohort study

Abubakar, Ibrahim; Drobniewski, Francis; Southern, Jo; Sitch, Alice; Jackson, Charlotte; Lipman, Marc; J Deeks, Jonathan; Griffiths, Chris; Bothamley, Graham; Lynn, William; J. Burgess, Helen; Mann, Bobby; Imran, Ambreen; Sridhar, Saranya; Tsou, Chuen-Yan; Nikolayevskyy, Vladyslav; Rees-Roberts, Melanie; Whitworth, Hilary; Min Kon, Onn; Haldar, Pranabashis; Kunst, Heinke; R. Anderson, Sarah; Hayward, Andrew; Watson, John; Milburn, Heather; Lalvani, Ajit; Adeboyeku, David; Bari, N; N. Barker, Juliet; Booth, Helen; Chua, Felix; Creer, Dean; Darmalingam, Mathina; Davidson, Richard; Dedicoat, Martin; Dunleavy, A; Figueroa, Javier; Haseldean, M; Johnson, Nicholas; Losewicz, S; Lord, Joanne; Moore-Gillon, J; Packe, G.E.; Pareek, Manish; Tiberi, Simon; Pozniak, Anton; Sanderson, Frances

doi:10.1016/s1473-3099(18)30355-4

Public

Prognostic value of interferon-γ release assays and tuberculin skin test in predicting the development of active tuberculosis (UK PREDICT TB): a prospective cohort study

Published in The Lancet Infectious Diseases • Aug 30, 2018

Authors:

Ibrahim Abubakar

Francis Drobniewski

Jo Southern

Abstract

BACKGROUND: Tackling tuberculosis requires testing and treatment of latent tuberculosis in high-risk groups. The aim of this study was to estimate the predictive values of the tuberculin skin test (TST) and two interferon-γ release assays (IGRAs) for the development of active tuberculosis in high-ri...

Subject

Tuberculosis

Medicine

Latent tuberculosis

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