MicroRNA-27a alleviates LPS-induced acute lung injury in mice via inhibiting inﬂammation and apoptosis through modulating TLR4/MyD88/NF-κB pathway

Ju, Min‐Jie; Liu, Bofei; He, Hongyu; Gu, Zhunyong; Liu, Yimei; Su, Ying; Zhu, Duming; Cang, Jing; Luo, Zhe

doi:10.1080/15384101.2018.1509635

Public

MicroRNA-27a alleviates LPS-induced acute lung injury in mice via inhibiting inﬂammation and apoptosis through modulating TLR4/MyD88/NF-κB pathway

Published in Cell Cycle • Aug 18, 2018

Authors:

Min‐Jie Ju

Bofei Liu

Hongyu He

Abstract

Acute lung injury (ALI) is a critical clinical condition with a high mortality rate, characterized with excessive uncontrolled inflammation and apoptosis. Recently, microRNAs (miRNAs) have been found to play crucial roles in the amelioration of various inflammation-induced diseases, including ALI. H...

Subject

Inflammation

TLR4

Apoptosis

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